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Dynamic enhancer partitioning instructs activation of a growth-related gene during exit from naïve pluripotency
During early mammalian development, the chromatin landscape undergoes profound transitions. The Zdbf2 gene—involved in growth control—provides a valuable model to study this window: upon exit from naïve pluripotency and prior to tissue differentiation, it undergoes a switch from a distal to a proxim...
Autores principales: | Greenberg, Maxim, Teissandier, Aurélie, Walter, Marius, Noordermeer, Daan, Bourc'his, Deborah |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488298/ https://www.ncbi.nlm.nih.gov/pubmed/30990414 http://dx.doi.org/10.7554/eLife.44057 |
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