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DksA–RNA polymerase interactions support new origin formation and DNA repair in Escherichia coli

The formation of new replication origins (cSDR) and repair of DNA double‐strand breaks (DSBs) in E. coli share a commonality. We find that the two processes require the RNAP‐associated factor, DksA. However, whereas cSDR also relies on (p)ppGpp, the alarmone molecule is dispensable for the repair of...

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Detalles Bibliográficos
Autores principales: Myka, Kamila K., Küsters, Kira, Washburn, Robert, Gottesman, Max E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488371/
https://www.ncbi.nlm.nih.gov/pubmed/30779388
http://dx.doi.org/10.1111/mmi.14227