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Identification of spatially associated subpopulations by combining scRNA-seq and sequential fluorescence in situ hybridization data
How intrinsic gene-regulatory networks interact with a cell’s spatial environment to define its identity remains poorly understood. Here we present an approach to distinguish intrinsic and extrinsic effects on global gene expression by integrating analysis of sequencing-based and imaging-based singl...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488461/ https://www.ncbi.nlm.nih.gov/pubmed/30371680 http://dx.doi.org/10.1038/nbt.4260 |