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Relative proteome quantification of alpha, beta, gamma and delta globin chains in early eluting peaks of Bio-Rad variant II(®) CE-HPLC of hemoglobin from healthy and beta-thalassemia subjects in Malaysia

This is the first report of QQQ-mass spectrometric identification and quantification of the Hb subunits, alpha, beta, delta and gamma globin peptides, derived from enzymatic-digestion of proteins in the early unknown peaks of the Bio-Rad cation-exchange chromatography of haemoglobin. The objectives...

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Detalles Bibliográficos
Autores principales: Abdullah, Uday Younis Hussein, Ibrahim, Hishamshah M., Jassim, Haitham Muhammed, Salleh, Mohamad Zaki, Kek, Teh Lay, Fakhruzzaman bin Noorizhab, Mohd Nur, Zilfalil, Bin Alwi, Wilairat, Prapin, Fucharoen, Suthat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488526/
https://www.ncbi.nlm.nih.gov/pubmed/31061897
http://dx.doi.org/10.1016/j.bbrep.2019.100635