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Coumarin derivatives as acetyl- and butyrylcholinestrase inhibitors: An in vitro, molecular docking, and molecular dynamics simulations study

Alzheimer's disease is an irreversible and progressive brain disease that can cause problems with memory and thinking skills. It is characterized by loss of cognitive ability and severe behavioral abnormalities, and could lead to death. Cholinesterases (ChEs) play a crucial role in the control...

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Detalles Bibliográficos
Autores principales: Abu-Aisheh, Marwa N., Al-Aboudi, Amal, Mustafa, Mohammad S., El-Abadelah, Mustafa M., Ali, Saman Yousuf, Ul-Haq, Zaheer, Mubarak, Mohammad S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488543/
https://www.ncbi.nlm.nih.gov/pubmed/31183424
http://dx.doi.org/10.1016/j.heliyon.2019.e01552