Glucose Restriction Promotes Osteocyte Specification by Activating a PGC-1α-Dependent Transcriptional Program

Osteocytes, the most abundant of bone cells, differentiate while they remain buried within the bone matrix. This encasement limits their access to nutrients and likely affects their differentiation, a process that remains poorly defined. Here, we show that restriction in glucose supply promotes the...

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Detalles Bibliográficos
Autores principales: Sánchez-de-Diego, Cristina, Artigas, Natalia, Pimenta-Lopes, Carolina, Valer, José Antonio, Torrejon, Benjamin, Gama-Pérez, Pau, Villena, Josep A., Garcia-Roves, Pablo M., Rosa, José Luis, Ventura, Francesc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488568/
https://www.ncbi.nlm.nih.gov/pubmed/31039455
http://dx.doi.org/10.1016/j.isci.2019.04.015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488568/
https://www.ncbi.nlm.nih.gov/pubmed/31039455
http://dx.doi.org/10.1016/j.isci.2019.04.015

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