Cortical circuit alterations precede motor impairments in Huntington’s disease mice

Huntington’s disease (HD) is a devastating hereditary movement disorder, characterized by degeneration of neurons in the striatum and cortex. Studies in human patients and mouse HD models suggest that disturbances of neuronal function in the neocortex play an important role in disease onset and prog...

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Detalles Bibliográficos
Autores principales: Burgold, Johanna, Schulz-Trieglaff, Elena Katharina, Voelkl, Kerstin, Gutiérrez-Ángel, Sara, Bader, Jakob Maximilian, Hosp, Fabian, Mann, Matthias, Arzberger, Thomas, Klein, Rüdiger, Liebscher, Sabine, Dudanova, Irina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488584/
https://www.ncbi.nlm.nih.gov/pubmed/31036840
http://dx.doi.org/10.1038/s41598-019-43024-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488584/
https://www.ncbi.nlm.nih.gov/pubmed/31036840
http://dx.doi.org/10.1038/s41598-019-43024-w

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