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Gut microbiota and butyrate level changes associated with the long-term administration of proton pump inhibitors to old rats

The association between adverse effects of PPI and gut microbiota in old age has yet to be elucidated. We assessed changes in the gut microbiota and butyrate levels following the long-term administration of PPIs to old rats and investigated their associations. F344 aged male rats were fed a PPI-supp...

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Detalles Bibliográficos
Autores principales: Lee, Sun Min, Kim, Nayoung, Nam, Ryoung Hee, Park, Ji Hyun, Choi, Soo In, Park, Young-Tae, Kim, Yeon-Ran, Seok, Yeong-Jae, Shin, Cheol Min, Lee, Dong Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488615/
https://www.ncbi.nlm.nih.gov/pubmed/31036935
http://dx.doi.org/10.1038/s41598-019-43112-x