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Flexible-to-rigid transition is central for substrate transport in the ABC transporter BmrA from Bacillus subtilis

ATP-binding-cassette (ABC) transporters are molecular pumps that translocate molecules across the cell membrane by switching between inward-facing and outward-facing states. To obtain a detailed understanding of their mechanism remains a challenge to structural biology, as these proteins are notorio...

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Detalles Bibliográficos
Autores principales: Lacabanne, Denis, Orelle, Cédric, Lecoq, Lauriane, Kunert, Britta, Chuilon, Claire, Wiegand, Thomas, Ravaud, Stéphanie, Jault, Jean-Michel, Meier, Beat H., Böckmann, Anja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488656/
https://www.ncbi.nlm.nih.gov/pubmed/31044174
http://dx.doi.org/10.1038/s42003-019-0390-x