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Flexible-to-rigid transition is central for substrate transport in the ABC transporter BmrA from Bacillus subtilis
ATP-binding-cassette (ABC) transporters are molecular pumps that translocate molecules across the cell membrane by switching between inward-facing and outward-facing states. To obtain a detailed understanding of their mechanism remains a challenge to structural biology, as these proteins are notorio...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488656/ https://www.ncbi.nlm.nih.gov/pubmed/31044174 http://dx.doi.org/10.1038/s42003-019-0390-x |