UM171 expands distinct types of myeloid and NK progenitors from human pluripotent stem cells

Scaling up blood cell production from hPSCs is critical to advancing hPSC technologies for blood transfusion, immunotherapy, and transplantation. Here we explored the potential of the HSC agonist pyrimido-indole derivative UM171, to expand hematopoietic progenitors (HPs) derived from hPSCs in chemic...

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Detalles Bibliográficos
Autores principales: Mesquitta, Walatta-Tseyon, Wandsnider, Matthew, Kang, HyunJun, Thomson, James, Moskvin, Oleg, Suknuntha, Kran, Slukvin, Igor I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488662/
https://www.ncbi.nlm.nih.gov/pubmed/31036928
http://dx.doi.org/10.1038/s41598-019-43054-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488662/
https://www.ncbi.nlm.nih.gov/pubmed/31036928
http://dx.doi.org/10.1038/s41598-019-43054-4

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