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Genetic risk score has added value over initial clinical grading stage in predicting disease progression in age-related macular degeneration

Several prediction models for progression of age-related macular degeneration (AMD) have been developed, but the added value of using genetic information in those models in addition to clinical characteristics is ambiguous. In this prospective cohort study, we explored the added value of genetics us...

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Detalles Bibliográficos
Autores principales: Heesterbeek, Thomas J., de Jong, Eiko K., Acar, Ilhan E., Groenewoud, Joannes M. M., Liefers, Bart, Sánchez, Clara I., Peto, Tunde, Hoyng, Carel B., Pauleikhoff, Daniel, Hense, Hans W., den Hollander, Anneke I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488669/
https://www.ncbi.nlm.nih.gov/pubmed/31036867
http://dx.doi.org/10.1038/s41598-019-43144-3