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CUT&Tag for efficient epigenomic profiling of small samples and single cells

Many chromatin features play critical roles in regulating gene expression. A complete understanding of gene regulation will require the mapping of specific chromatin features in small samples of cells at high resolution. Here we describe Cleavage Under Targets and Tagmentation (CUT&Tag), an enzy...

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Detalles Bibliográficos
Autores principales: Kaya-Okur, Hatice S., Wu, Steven J., Codomo, Christine A., Pledger, Erica S., Bryson, Terri D., Henikoff, Jorja G., Ahmad, Kami, Henikoff, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488672/
https://www.ncbi.nlm.nih.gov/pubmed/31036827
http://dx.doi.org/10.1038/s41467-019-09982-5