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Downregulation of CYB5D2 is associated with breast cancer progression

We report here that CYB5D2 is associated with tumor suppression function in breast cancer (BC). CYB5D2 expression was significantly reduced in tamoxifen resistant MCF7 cells and in MCF7 cell-derived xenografts treated with TAM. CYB5D2 overexpression induced apoptosis in MCF7 cells; CYB5D2 knockdown...

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Detalles Bibliográficos
Autores principales: Ojo, Diane, Rodriguez, David, Wei, Fengxiang, Bane, Anita, Tang, Damu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488675/
https://www.ncbi.nlm.nih.gov/pubmed/31036830
http://dx.doi.org/10.1038/s41598-019-43006-y