MicroRNA-186 targets SKP2 to induce p27(Kip1)-mediated pituitary tumor cell cycle deregulation and modulate cell proliferation

Pituitary tumors are usually benign but can occasionally exhibit hormonal and proliferative behaviors. Dysregulation of the G1/S restriction point largely contributes to the over-proliferation of pituitary tumor cells. F-box protein S-phase kinase-interacting protein-2 (SKP2) reportedly targets and...

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Detalles Bibliográficos
Autores principales: He, Zongze, Chen, Longyi, Wang, Qi, Yin, Cheng, Hu, Junting, Hu, Xiao, Fei, Fan, Tang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488709/
https://www.ncbi.nlm.nih.gov/pubmed/31080348
http://dx.doi.org/10.4196/kjpp.2019.23.3.171

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488709/
https://www.ncbi.nlm.nih.gov/pubmed/31080348
http://dx.doi.org/10.4196/kjpp.2019.23.3.171

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