Glucagon Receptor Antagonism Ameliorates Progression of Heart Failure

Mice were treated with a fully human monoclonal glucagon receptor antagonistic antibody REMD2.59 following myocardial infarction or pressure overload. REMD2.59 treatment blunted cardiac hypertrophy and fibrotic remodeling, and attenuated contractile dysfunction at 4 weeks after myocardial infarction...

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Detalles Bibliográficos
Autores principales: Gao, Chen, Ren, Shuxun Vincent, Yu, Junyi, Baal, Ulysis, Thai, Dung, Lu, John, Zeng, Chunyu, Yan, Hai, Wang, Yibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
PRECLINICAL RESEARCH
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488764/
https://www.ncbi.nlm.nih.gov/pubmed/31061918
http://dx.doi.org/10.1016/j.jacbts.2018.11.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488764/
https://www.ncbi.nlm.nih.gov/pubmed/31061918
http://dx.doi.org/10.1016/j.jacbts.2018.11.001

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