Fast and accurate relatedness estimation from high-throughput sequencing data in the presence of inbreeding

BACKGROUND: The estimation of relatedness between pairs of possibly inbred individuals from high-throughput sequencing (HTS) data has previously not been possible for samples where we cannot obtain reliable genotype calls, as in the case of low-coverage data. RESULTS: We introduce ngsRelateV2, a maj...

Descripción completa

Detalles Bibliográficos
Autores principales: Hanghøj, Kristian, Moltke, Ida, Andersen, Philip Alstrup, Manica, Andrea, Korneliussen, Thorfinn Sand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Technical Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488770/
https://www.ncbi.nlm.nih.gov/pubmed/31042285
http://dx.doi.org/10.1093/gigascience/giz034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488770/
https://www.ncbi.nlm.nih.gov/pubmed/31042285
http://dx.doi.org/10.1093/gigascience/giz034

Ejemplares similares