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Fast and accurate relatedness estimation from high-throughput sequencing data in the presence of inbreeding
BACKGROUND: The estimation of relatedness between pairs of possibly inbred individuals from high-throughput sequencing (HTS) data has previously not been possible for samples where we cannot obtain reliable genotype calls, as in the case of low-coverage data. RESULTS: We introduce ngsRelateV2, a maj...
Autores principales: | Hanghøj, Kristian, Moltke, Ida, Andersen, Philip Alstrup, Manica, Andrea, Korneliussen, Thorfinn Sand |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488770/ https://www.ncbi.nlm.nih.gov/pubmed/31042285 http://dx.doi.org/10.1093/gigascience/giz034 |
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