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Celecoxib Is Associated With Dystrophic Calcification and Aortic Valve Stenosis

Calcific aortic valve disease is a progressive fibrocalcific process that can only be treated with valve replacement. Cadherin-11 has recently been identified as a potential therapeutic target for calcific aortic valve disease. The already approved drug celecoxib, a cyclooxygenase-2 inhibitor, binds...

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Detalles Bibliográficos
Autores principales: Bowler, Meghan A., Raddatz, Michael A., Johnson, Camryn L., Lindman, Brian R., Merryman, W. David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488810/
https://www.ncbi.nlm.nih.gov/pubmed/31061914
http://dx.doi.org/10.1016/j.jacbts.2018.12.003