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Local intravascular delivery of low-density-lipoprotein cholesterol corresponds with increased intimal thickening in a healthy porcine coronary model. A prelude to development of a model of atherosclerosis

INTRODUCTION: Preclinical, vascular response studies are limited due to lack of underlying disease. The available cholesterol-diet-based and genetic atherosclerotic models are not satisfactory due to long breeding, unpredictable lesion formation, low plaque volume and degree of stenosis. AIM: To eva...

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Detalles Bibliográficos
Autores principales: Buszman, Piotr P., Orlik, Bartlomiej, Milewski, Krzysztof P., Roleder, Tomasz, Jelonek, Michał, Polczyk, Filip, Kolodgie, Frank D., Jankowski, Maciej, Virmani, Renu, Buszman, Paweł E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488843/
https://www.ncbi.nlm.nih.gov/pubmed/31043989
http://dx.doi.org/10.5114/aic.2019.83774