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Cell cycle activation contributes to isoflurane‐induced neurotoxicity in the developing brain and the protective effect of CR8

AIMS: It is well established that exposure of common anesthetic isoflurane in early life can induce neuronal apoptosis and long‐lasting cognitive deficit, but the underlying mechanisms were not well understood. The cell cycle protein Cyclin B1 plays an important role in the survival of postmitotic n...

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Detalles Bibliográficos
Autores principales: Huang, Bao‐Yi, Huang, Hong‐Bing, Zhang, Zhi‐Jing, Liu, Zhi‐Gang, Luo, Jun, Liu, Min, Luo, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488878/
https://www.ncbi.nlm.nih.gov/pubmed/30676695
http://dx.doi.org/10.1111/cns.13090