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The PPARα agonist fenofibrate attenuates disruption of dopamine function in a maternal immune activation rat model of schizophrenia

AIMS: Prenatal maternal immune activation (MIA) is associated with a risk to develop schizophrenia and affects dopamine systems in the ventral tegmental area (VTA), key region in the neurobiology of psychoses. Considering the well‐described sex differences in schizophrenia, we investigated whether s...

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Detalles Bibliográficos
Autores principales: De Felice, Marta, Melis, Miriam, Aroni, Sonia, Muntoni, Anna Lisa, Fanni, Silvia, Frau, Roberto, Devoto, Paola, Pistis, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488881/
https://www.ncbi.nlm.nih.gov/pubmed/30461214
http://dx.doi.org/10.1111/cns.13087