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Baicalin mitigates cognitive impairment and protects neurons from microglia‐mediated neuroinflammation via suppressing NLRP3 inflammasomes and TLR4/NF‐κB signaling pathway

AIMS: Baicalin (BAI), a flavonoid compound isolated from the root of Scutellaria baicalensis Georgi, has been established to have potent anti‐inflammation and neuroprotective properties; however, its effects during Alzheimer's disease (AD) treatment have not been well studied. This study aimed...

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Detalles Bibliográficos
Autores principales: Jin, Xin, Liu, Ming‐Yan, Zhang, Dong‐Fang, Zhong, Xin, Du, Ke, Qian, Ping, Yao, Wei‐Fan, Gao, Hua, Wei, Min‐Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488900/
https://www.ncbi.nlm.nih.gov/pubmed/30676698
http://dx.doi.org/10.1111/cns.13086