IL‐2mAb reduces demyelination after focal cerebral ischemia by suppressing CD8(+) T cells

AIMS: Demyelination, one of the major pathological changes of white matter injury, is closely related to T‐cell–mediated immune responses. Thus, we investigate the role of an IL‐2 monoclonal antibody (IL‐2mAb, JES6‐1) in combatting demyelination during the late phase of stroke. METHODS: IL‐2mAb or I...

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Detalles Bibliográficos
Autores principales: Zhou, Yu‐Xi, Wang, Xin, Tang, Dan, Li, Yan, Jiao, Ying‐Fu, Gan, Yu, Hu, Xiao‐Ming, Yang, Li‐Qun, Yu, Wei‐Feng, Stetler, Ruth Anne, Li, Pei‐Ying, Wen, Da‐Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488908/
https://www.ncbi.nlm.nih.gov/pubmed/30444079
http://dx.doi.org/10.1111/cns.13084

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488908/
https://www.ncbi.nlm.nih.gov/pubmed/30444079
http://dx.doi.org/10.1111/cns.13084

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