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WYE-354 restores Adriamycin sensitivity in multidrug-resistant acute myeloid leukemia cell lines

Multidrug resistance (MDR) is a major reason for the failure of acute myeloid leukemia (AML) therapy. Agents that reverse MDR and sensitize AML cells to chemotherapy are of great clinical significance. The present study developed Adriamycin (Adr)-resistant cell lines, namely K562/Adr200 and K562/Adr...

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Detalles Bibliográficos
Autores principales: Ibrahim, Sara M., Bakhashab, Sherin, Ilyas, Asad M., Pushparaj, Peter N., Karim, Sajjad, Khan, Jalaluddin A., Abuzenadah, Adel M., Chaudhary, Adeel G., Al-Qahtani, Muhammed H., Ahmed, Farid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6489006/
https://www.ncbi.nlm.nih.gov/pubmed/30942458
http://dx.doi.org/10.3892/or.2019.7093