Inhibition of neddylation modification by MLN4924 sensitizes hepatocellular carcinoma cells to sorafenib

Sorafenib remains the standard care for patients with hepatocellular carcinoma (HCC) even though it has low antitumor efficacy. Protein neddylation is abnormally activated in many types of human cancer. However, whether dysregulation of neddylation is involved in HCC progression and whether targetin...

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Detalles Bibliográficos
Autores principales: Yang, Zelong, Zhang, Jie, Lin, Xiaotong, Wu, Di, Li, Guixi, Zhong, Chunlian, Fang, Lei, Jiang, Peng, Yin, Liangyu, Zhang, Leida, Bie, Ping, Xie, Chuan-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6489087/
https://www.ncbi.nlm.nih.gov/pubmed/31002342
http://dx.doi.org/10.3892/or.2019.7098

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6489087/
https://www.ncbi.nlm.nih.gov/pubmed/31002342
http://dx.doi.org/10.3892/or.2019.7098

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