A novel spheroid-based co-culture model mimics loss of keratinocyte differentiation, melanoma cell invasion, and drug-induced selection of ABCB5-expressing cells

BACKGROUND: Different 3D-cell culture approaches with varying degrees of complexity have been developed to serve as melanoma models for drug testing or mechanistic studies. While these 3D-culture initiatives are already often superior to classical 2D approaches, they are either composed of only mela...

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Detalles Bibliográficos
Autores principales: Klicks, Julia, Maßlo, Christoph, Kluth, Andreas, Rudolf, Rüdiger, Hafner, Mathias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6489189/
https://www.ncbi.nlm.nih.gov/pubmed/31035967
http://dx.doi.org/10.1186/s12885-019-5606-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6489189/
https://www.ncbi.nlm.nih.gov/pubmed/31035967
http://dx.doi.org/10.1186/s12885-019-5606-4

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