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Vimentin expression is retained in erythroid cells differentiated from human iPSC and ESC and indicates dysregulation in these cells early in differentiation

BACKGROUND: Pluripotent stem cells are attractive progenitor cells for the generation of erythroid cells in vitro as have expansive proliferative potential. However, although embryonic (ESC) and induced pluripotent (iPSC) stem cells can be induced to undergo erythroid differentiation, the majority o...

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Detalles Bibliográficos
Autores principales: Trakarnsanga, Kongtana, Ferguson, Daniel, Daniels, Deborah E., Griffiths, Rebecca E., Wilson, Marieangela C., Mordue, Kathryn E., Gartner, Abi, Andrienko, Tatyana N., Calvert, Annabel, Condie, Alison, McCahill, Angela, Mountford, Joanne C., Toye, Ashley M., Anstee, David J., Frayne, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6489253/
https://www.ncbi.nlm.nih.gov/pubmed/31036072
http://dx.doi.org/10.1186/s13287-019-1231-z