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Dual prognostic role of 2-oxoglutarate-dependent oxygenases in ten cancer types: implications for cell cycle regulation and cell adhesion maintenance

BACKGROUND: Tumor hypoxia is associated with metastasis and resistance to chemotherapy and radiotherapy. Genes involved in oxygen-sensing are clinically relevant and have significant implications for prognosis. In this study, we examined the pan-cancer prognostic significance of oxygen-sensing genes...

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Detalles Bibliográficos
Autores principales: Chang, Wai Hoong, Forde, Donall, Lai, Alvina G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6489267/
https://www.ncbi.nlm.nih.gov/pubmed/31036064
http://dx.doi.org/10.1186/s40880-019-0369-5