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Sustained interleukin-10 delivery reduces inflammation and improves motor function after spinal cord injury

BACKGROUND: The anti-inflammatory cytokine interleukin-10 (IL-10) has been explored previously as a treatment method for spinal cord injury (SCI) due to its ability to attenuate pro-inflammatory cytokines and reduce apoptosis. Primary limitations when using systemic injections of IL-10 are that it i...

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Detalles Bibliográficos
Autores principales: Hellenbrand, Daniel J., Reichl, Kaitlyn A., Travis, Benjamin J., Filipp, Mallory E., Khalil, Andrew S., Pulito, Domenic J., Gavigan, Ashley V., Maginot, Elizabeth R., Arnold, Mitchell T., Adler, Alexander G., Murphy, William L., Hanna, Amgad S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6489327/
https://www.ncbi.nlm.nih.gov/pubmed/31039819
http://dx.doi.org/10.1186/s12974-019-1479-3