Cargando…

Sustained interleukin-10 delivery reduces inflammation and improves motor function after spinal cord injury

BACKGROUND: The anti-inflammatory cytokine interleukin-10 (IL-10) has been explored previously as a treatment method for spinal cord injury (SCI) due to its ability to attenuate pro-inflammatory cytokines and reduce apoptosis. Primary limitations when using systemic injections of IL-10 are that it i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hellenbrand, Daniel J., Reichl, Kaitlyn A., Travis, Benjamin J., Filipp, Mallory E., Khalil, Andrew S., Pulito, Domenic J., Gavigan, Ashley V., Maginot, Elizabeth R., Arnold, Mitchell T., Adler, Alexander G., Murphy, William L., Hanna, Amgad S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6489327/ https://www.ncbi.nlm.nih.gov/pubmed/31039819 http://dx.doi.org/10.1186/s12974-019-1479-3

Ejemplares similares

Differences in neuroplasticity after spinal cord injury in varying animal models and humans
por: Filipp, Mallory E., et al.
Publicado: (2019)

Treating spinal cord injury via sustained drug delivery from calcium phosphate coatings
por: Hellenbrand, Daniel J., et al.
Publicado: (2016)

Inflammation after spinal cord injury: a review of the critical timeline of signaling cues and cellular infiltration
por: Hellenbrand, Daniel J., et al.
Publicado: (2021)

Glial cell line-derived neurotrophic factor as a treatment after spinal cord injury
por: Ortmann, Stephen D., et al.
Publicado: (2018)

Gait analysis in swine, sheep, and goats after neurologic injury: a literature review
por: Sveum, Jacob W., et al.
Publicado: (2023)

The Effect of a Curved Non-Motorized Treadmill on Running Gait Length, Imbalance and Stride Angle
por: Hatchett, Andrew, et al.
Publicado: (2018)

Predictors of interleukin-33 and thymic stromal lymphopoietin levels in cord blood
por: Ashley-Martin, Jillian, et al.
Publicado: (2015)

Motor neurons control blood vessel patterning in the developing spinal cord
por: Himmels, Patricia, et al.
Publicado: (2017)

Motor neurobiology of the spinal cord /
Publicado: (2001)

Glioma Immunotherapy: Advances and Challenges for Spinal Cord Gliomas
por: Grady, Clare, et al.
Publicado: (2022)

Restoration of motor function following spinal cord injury via optimal control of intraspinal microstimulation: toward a next generation closed-loop neural prosthesis
por: Grahn, Peter J., et al.
Publicado: (2014)

Functional recovery after peripheral nerve injury via sustained growth factor delivery from mineral-coated microparticles
por: Hellenbrand, Daniel J., et al.
Publicado: (2020)

Interleukin-27: a novel biomarker in predicting bacterial infection among the critically ill
por: Hanna, William J., et al.
Publicado: (2015)

Neuroprotective effects of interleukin 10 in spinal cord injury
por: Li, Juan, et al.
Publicado: (2023)

Feasibility and utility of transcutaneous spinal cord stimulation combined with walking-based therapy for people with motor incomplete spinal cord injury
por: McHugh, Liza V., et al.
Publicado: (2020)

Changing Perspectives on Pediatric Human Papillomavirus (HPV) Vaccination among Dental Students and Residents Reveals Recent Increase in Vaccine Hesitancy
por: Maginot, Rebecca, et al.
Publicado: (2022)

Revisiting IL-1β: Linking Metainflammation to Diastolic Dysfunction
por: Filipp, Mallory, et al.
Publicado: (2023)

The impact of health care provider relationships and communication dynamics on urinary tract infection management and antibiotic utilization for long-term care facility residents treated in the emergency department: A qualitative study
por: Valmadrid, Luke Carmichael, et al.
Publicado: (2021)

From cortex to cord: motor circuit plasticity after spinal cord injury
por: Brown, Andrew R., et al.
Publicado: (2019)

Neurophysiology of epidurally evoked spinal cord reflexes in clinically motor-complete posttraumatic spinal cord injury
por: Vargas Luna, Jose Luis, et al.
Publicado: (2021)

Cellular Sources and Neuroprotective Roles of Interleukin-10 in the Facial Motor Nucleus after Axotomy
por: Runge, Elizabeth M., et al.
Publicado: (2022)

Spinal Cord Imaging Markers and Recovery of Volitional Leg Movement With Spinal Cord Epidural Stimulation in Individuals With Clinically Motor Complete Spinal Cord Injury
por: Rejc, Enrico, et al.
Publicado: (2020)

Spinal cord epidural stimulation for motor and autonomic function recovery after chronic spinal cord injury: A case series and technical note
por: Boakye, Maxwell, et al.
Publicado: (2023)

Just Sinus Bradycardia or Something More Serious?
por: Egan, Kelly R., et al.
Publicado: (2013)

Motor recovery after activity-based training with spinal cord epidural stimulation in a chronic motor complete paraplegic
por: Rejc, Enrico, et al.
Publicado: (2017)

Orexinergic Modulation of Spinal Motor Activity in the Neonatal Mouse Spinal Cord
por: Biswabharati, Sukanya, et al.
Publicado: (2018)

Endothelial PlexinD1 signaling instructs spinal cord vascularization and motor neuron development
por: Vieira, José Ricardo, et al.
Publicado: (2022)

Extensive Fusion of Mitochondria in Spinal Cord Motor Neurons
por: Owens, Geoffrey C., et al.
Publicado: (2012)

Can motor volition be extracted from the spinal cord?
por: Prasad, Abhishek, et al.
Publicado: (2012)

An Optogenetic Demonstration of Motor Modularity in the Mammalian Spinal Cord
por: Caggiano, Vittorio, et al.
Publicado: (2016)

Plastic Changes in the Spinal Cord in Motor Neuron Disease
por: Fornai, Francesco, et al.
Publicado: (2014)

Interleukin-25 is detrimental for recovery after spinal cord injury in mice
por: Dooley, Dearbhaile, et al.
Publicado: (2016)

Interleukins Profiling in Umbilical Cord Mesenchymal Stem Cell-Derived Secretome
por: Chouw, Angliana, et al.
Publicado: (2022)

Alterations in Motor Cortical Representation of Muscles Following Incomplete Spinal Cord Injury in Humans
por: Fassett, Hunter J., et al.
Publicado: (2018)

Resolution of Metastatic Subungal Eccrine Porocarcinoma Treated with Intralesional Interleukin-2
por: Drohan, Ashley, et al.
Publicado: (2020)

Jagged2 controls the generation of motor neuron and oligodendrocyte progenitors in the ventral spinal cord
por: Rabadán, M A, et al.
Publicado: (2012)

Reference Values for Interleukin-6 and Interleukin-8 in Cord Blood of Healthy Term Neonates and Their Association with Stress-Related Perinatal Factors
por: Barug, Daan, et al.
Publicado: (2014)

Transfusion or Timing: The Role of Blood Volume in Delayed Cord Clamping During the Cardiovascular Transition at Birth
por: Stenning, Fiona J., et al.
Publicado: (2019)

Recruitment order of motor neurons promoted by epidural stimulation in individuals with spinal cord injury
por: Ibáñez, Jaime, et al.
Publicado: (2021)

Neurophysiological Characterization of Motor Recovery in Acute Spinal Cord Injury
por: McKay, WB, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_59cvftd3jfuk6ej55kv063fum3