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Two New Plasmid Post-segregational Killing Mechanisms for the Implementation of Synthetic Gene Networks in Escherichia coli

Plasmids are the workhorse of both industrial biotechnology and synthetic biology, but ensuring they remain in bacterial cells is a challenge. Antibiotic selection cannot be used to stabilize plasmids in most real-world applications, and inserting dynamical gene networks into the genome remains chal...

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Detalles Bibliográficos
Autores principales: Fedorec, Alex J.H., Ozdemir, Tanel, Doshi, Anjali, Ho, Yan-Kay, Rosa, Luca, Rutter, Jack, Velazquez, Oscar, Pinheiro, Vitor B., Danino, Tal, Barnes, Chris P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6489366/
https://www.ncbi.nlm.nih.gov/pubmed/30954530
http://dx.doi.org/10.1016/j.isci.2019.03.019