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Dorsal Raphe Dual Serotonin-Glutamate Neurons Drive Reward by Establishing Excitatory Synapses on VTA Mesoaccumbens Dopamine Neurons

Dorsal raphe (DR) serotonin neurons provide a major input to the ventral tegmental area (VTA). Here, we show that DR serotonin transporter (SERT) neurons establish both asymmetric and symmetric synapses on VTA dopamine neurons, but most of these synapses are asymmetric. Moreover, the DR-SERT termina...

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Detalles Bibliográficos
Autores principales: Wang, Hui-Ling, Zhang, Shiliang, Qi, Jia, Wang, Huikun, Cachope, Roger, Mejias-Aponte, Carlos A., Gomez, Jorge A., Mateo-Semidey, Gabriel E., Beaudoin, Gerard M.J., Paladini, Carlos A., Cheer, Joseph F., Morales, Marisela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6489450/
https://www.ncbi.nlm.nih.gov/pubmed/30699344
http://dx.doi.org/10.1016/j.celrep.2019.01.014