Antiproliferative Effects of Matricine in Gemcitabine-Resistant Human Pancreatic Carcinoma Cells Are Mediated via Mitochondrial-Mediated Apoptosis, Inhibition of Cell Migration, Invasion Suppression, and Mammalian Target of Rapamycin (mTOR)-TOR/PI3K/AKT Signalling Pathway

BACKGROUND: Pancreatic cancer is a major cause of mortality worldwide. Inefficient drugs, their adverse effects, and the development of drug resistance make it difficult to curb the growing incidence of pancreatic cancer. Against this backdrop, the development new drug regimens with no or negligible...

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Detalles Bibliográficos
Autores principales: Fang, Kaifeng, Wang, Li, Chen, LuJia, Liu, Tao, Fang, Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2019
Materias:
Lab/In Vitro Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6489536/
https://www.ncbi.nlm.nih.gov/pubmed/31005960
http://dx.doi.org/10.12659/MSM.914244

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6489536/
https://www.ncbi.nlm.nih.gov/pubmed/31005960
http://dx.doi.org/10.12659/MSM.914244

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