Tetramethylpyrazine attenuated bupivacaine-induced neurotoxicity in SH-SY5Y cells through regulating apoptosis, autophagy and oxidative damage

Background: Bupivacaine (BUP) acts as a local anesthetic, which is extensively used for clinical patients but could generate neurotoxicity in neurons. Tetramethylpyrazine (TET) exhibits strong neuron protective effects against neurotoxicity. Hence, we investigate the effect of TET on BUP-induced neu...

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Detalles Bibliográficos
Autores principales: Wang, Shouliang, Xia, Bin, Qiao, Zonglei, Duan, Lian, Wang, Gongming, Meng, Wenjun, Liu, Zhifei, Wang, Yu, Zhang, Mengyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6489565/
https://www.ncbi.nlm.nih.gov/pubmed/31114159
http://dx.doi.org/10.2147/DDDT.S196172

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6489565/
https://www.ncbi.nlm.nih.gov/pubmed/31114159
http://dx.doi.org/10.2147/DDDT.S196172

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