G1/S cell cycle regulators mediate effects of circadian dysregulation on tumor growth and provide targets for timed anticancer treatment

Circadian disruption has multiple pathological consequences, but the underlying mechanisms are largely unknown. To address such mechanisms, we subjected transformed cultured cells to chronic circadian desynchrony (CCD), mimicking a chronic jet-lag scheme, and assayed a range of cellular functions. T...

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Detalles Bibliográficos
Autores principales: Lee, Yool, Lahens, Nicholas F., Zhang, Shirley, Bedont, Joseph, Field, Jeffrey M., Sehgal, Amita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6490878/
https://www.ncbi.nlm.nih.gov/pubmed/31039152
http://dx.doi.org/10.1371/journal.pbio.3000228

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6490878/
https://www.ncbi.nlm.nih.gov/pubmed/31039152
http://dx.doi.org/10.1371/journal.pbio.3000228

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