Early existence and biochemical evolution characterise acutely synaptotoxic PrP(Sc)

Although considerable evidence supports that misfolded prion protein (PrP(Sc)) is the principal component of “prions”, underpinning both transmissibility and neurotoxicity, clear consensus around a number of fundamental aspects of pathogenesis has not been achieved, including the time of appearance...

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Detalles Bibliográficos
Autores principales: Foliaki, Simote Totauhelotu, Lewis, Victoria, Islam, Abu Mohammed Taufiqual, Ellett, Laura Jane, Senesi, Matteo, Finkelstein, David Isaac, Roberts, Blaine, Lawson, Victoria A., Adlard, Paul Anthony, Collins, Steven John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6490942/
https://www.ncbi.nlm.nih.gov/pubmed/30970042
http://dx.doi.org/10.1371/journal.ppat.1007712

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6490942/
https://www.ncbi.nlm.nih.gov/pubmed/30970042
http://dx.doi.org/10.1371/journal.ppat.1007712

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