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Comprehensive mapping of adaptation of the avian influenza polymerase protein PB2 to humans

Viruses like influenza are infamous for their ability to adapt to new hosts. Retrospective studies of natural zoonoses and passaging in the lab have identified a modest number of host-adaptive mutations. However, it is unclear if these mutations represent all ways that influenza can adapt to a new h...

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Detalles Bibliográficos
Autores principales: Soh, YQ Shirleen, Moncla, Louise H, Eguia, Rachel, Bedford, Trevor, Bloom, Jesse D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491042/
https://www.ncbi.nlm.nih.gov/pubmed/31038123
http://dx.doi.org/10.7554/eLife.45079