Discovery of therapeutic agents for prostate cancer using genome-scale metabolic modeling and drug repositioning

BACKGROUND: Genome-scale metabolic models (GEMs) offer insights into cancer metabolism and have been used to identify potential biomarkers and drug targets. Drug repositioning is a time- and cost-effective method of drug discovery that can be applied together with GEMs for effective cancer treatment...

Descripción completa

Detalles Bibliográficos
Autores principales: Turanli, Beste, Zhang, Cheng, Kim, Woonghee, Benfeitas, Rui, Uhlen, Mathias, Arga, Kazim Yalcin, Mardinoglu, Adil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491384/
https://www.ncbi.nlm.nih.gov/pubmed/30905848
http://dx.doi.org/10.1016/j.ebiom.2019.03.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491384/
https://www.ncbi.nlm.nih.gov/pubmed/30905848
http://dx.doi.org/10.1016/j.ebiom.2019.03.009

Ejemplares similares