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Patient-specific organotypic blood vessels as an in vitro model for anti-angiogenic drug response testing in renal cell carcinoma

BACKGROUND: Anti-angiogenic treatment failure is often attributed to drug resistance, unsuccessful drug delivery, and tumor heterogeneity. Recent studies have speculated that anti-angiogenic treatments may fail due to characteristics inherent to tumor-associated blood vessels. Tumor-associated blood...

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Detalles Bibliográficos
Autores principales: Jiménez-Torres, José A., Virumbrales-Muñoz, María, Sung, Kyung E., Lee, Moon Hee, Abel, E. Jason, Beebe, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491391/
https://www.ncbi.nlm.nih.gov/pubmed/30902740
http://dx.doi.org/10.1016/j.ebiom.2019.03.026