Cargando…

Patient-specific organotypic blood vessels as an in vitro model for anti-angiogenic drug response testing in renal cell carcinoma

BACKGROUND: Anti-angiogenic treatment failure is often attributed to drug resistance, unsuccessful drug delivery, and tumor heterogeneity. Recent studies have speculated that anti-angiogenic treatments may fail due to characteristics inherent to tumor-associated blood vessels. Tumor-associated blood...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jiménez-Torres, José A., Virumbrales-Muñoz, María, Sung, Kyung E., Lee, Moon Hee, Abel, E. Jason, Beebe, David J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Research paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491391/ https://www.ncbi.nlm.nih.gov/pubmed/30902740 http://dx.doi.org/10.1016/j.ebiom.2019.03.026

Ejemplares similares

Models of Renal Cell Carcinoma Used to Investigate Molecular Mechanisms and Develop New Therapeutics
por: Shapiro, Daniel D., et al.
Publicado: (2022)

Microfluidic model of ductal carcinoma in situ with 3D, organotypic structure
por: Bischel, Lauren L, et al.
Publicado: (2015)

Primary Head and Neck Tumour-Derived Fibroblasts Promote Lymphangiogenesis in a Lymphatic Organotypic Co-culture Model
por: Lugo-Cintrón, Karina M., et al.
Publicado: (2021)

The SUMO protease SENP1 promotes aggressive behaviors of high HIF2α expressing renal cell carcinoma cells
por: Lee, Moon Hee, et al.
Publicado: (2022)

Toward improved in vitro models of human cancer
por: Ayuso, Jose M., et al.
Publicado: (2021)

Microbial volatile communication in human organotypic lung models
por: Barkal, Layla J., et al.
Publicado: (2017)

Mural Cell Associated VEGF Is Required for Organotypic Vessel Formation
por: Evensen, Lasse, et al.
Publicado: (2009)

Effective reconstruction of functional organotypic kidney spheroid for in vitro nephrotoxicity studies
por: Kang, Hyun Mi, et al.
Publicado: (2019)

Vessel Architectural Imaging Identifies Cancer Patient Responders to Anti-angiogenic Therapy
por: Emblem, Kyrre E., et al.
Publicado: (2013)

Organotypic brain slice cultures as a model to study angiogenesis of brain vessels
por: Hutter-Schmid, Bianca, et al.
Publicado: (2015)

Vessel co-option mediates resistance to anti-angiogenic therapy in liver metastases
por: Frentzas, Sophia, et al.
Publicado: (2016)

Lack of functional normalisation of tumour vessels following anti-angiogenic therapy in glioblastoma
por: Obad, Nina, et al.
Publicado: (2017)

Phosphatase inhibitors with anti-angiogenic effect in vitro
por: SYLVEST, LENE, et al.
Publicado: (2010)

A Vascular Endothelial Growth Factor-Dependent Sprouting Angiogenesis Assay Based on an In Vitro Human Blood Vessel Model for the Study of Anti-Angiogenic Drugs
por: Pauty, Joris, et al.
Publicado: (2017)

Alternative transcription of a shorter, non-anti-angiogenic thrombospondin-2 variant in cancer-associated blood vessels
por: Roudnicky, Filip, et al.
Publicado: (2018)

Nucleolin expressed at the cell surface is a marker of endothelial cells in angiogenic blood vessels
por: Christian, Sven, et al.
Publicado: (2003)

Organotypic cocultures as skin equivalents: A complex and sophisticated in vitro system
por: Stark, Hans-Jürgen, et al.
Publicado: (2004)

In Vitro and In Vivo Anti-Angiogenic Activities of Panduratin A
por: Lai, Siew-Li, et al.
Publicado: (2012)

Vessel co-option in primary human tumors and metastases: an obstacle to effective anti-angiogenic treatment?
por: Donnem, Tom, et al.
Publicado: (2013)

Evidence for the Effects of Xanthohumol in Disrupting Angiogenic, but not Stable Vessels
por: Negrão, Rita, et al.
Publicado: (2007)

Immune consequences of anti-angiogenic therapyin renal cell carcinoma
por: Brodaczewska, Klaudia K., et al.
Publicado: (2018)

In vitro three-dimensional organotypic culture models of the oral mucosa
por: Klausner, Mitchell, et al.
Publicado: (2021)

Advanced Organotypic In Vitro Model Systems for Host–Microbial Coculture
por: Kim, Raehyun
Publicado: (2023)

A role for microfluidic systems in precision medicine
por: Ayuso, Jose M., et al.
Publicado: (2022)

Changes in tumour vessel density upon treatment with anti-angiogenic agents: relationship with response and resistance to therapy
por: Vasudev, N S, et al.
Publicado: (2013)

Anterior gradient 2 as a supervisory marker for tumor vessel normalization induced by anti-angiogenic treatment
por: Pan, Fan, et al.
Publicado: (2018)

On the preservation of vessel bifurcations during flow-mediated angiogenic remodelling
por: Edgar, Lowell T., et al.
Publicado: (2021)

Angiogenesis in mammary Paget disease: histopathological analyses of blood vessel density and angiogenic factors
por: Akishima-Fukasawa, Yuri, et al.
Publicado: (2020)

Angiogenic signaling pathways and anti-angiogenic therapy for cancer
por: Liu, Zhen-Ling, et al.
Publicado: (2023)

Decrease of Pro-Angiogenic Monocytes Predicts Clinical Response to Anti-Angiogenic Treatment in Patients with Metastatic Renal Cell Carcinoma
por: Oudard, Stephane, et al.
Publicado: (2021)

Correlation of in vitro infiltration with glioma histological type in organotypic brain slices
por: Palfi, S, et al.
Publicado: (2004)

A human population-based organotypic in vitro model for cardiotoxicity screening
por: Grimm, Fabian A., et al.
Publicado: (2018)

An organotypic slice culture to study the formation of calyx of Held synapses in-vitro
por: Kronander, Elin, et al.
Publicado: (2017)

Immuno-Expression of Endoglin and Smooth Muscle Actin in the Vessels of Brain Metastases. Is There a Rational for Anti-Angiogenic Therapy?
por: Barresi, Valeria, et al.
Publicado: (2014)

Studies on the anti-angiogenic effect of Marsdenia tenacissima extract in vitro and in vivo
por: HUANG, ZHENGRONG, et al.
Publicado: (2013)

Design of Anti-Angiogenic Peptidomimetics and Evaluation their Biological Activity by In Vitro Assays
por: Ghadam, Mona, et al.
Publicado: (2020)

Biomarkers for Anti-Angiogenic Therapy in Cancer
por: Wehland, Markus, et al.
Publicado: (2013)

Collagen hydrogels loaded with fibroblast growth factor-2 as a bridge to repair brain vessels in organotypic brain slices
por: Ucar, Buket, et al.
Publicado: (2020)

“Vessels in the Storm”: Searching for Prognostic and Predictive Angiogenic Factors in Colorectal Cancer
por: Angelucci, Adriano, et al.
Publicado: (2018)

Nanoparticle Delivery of Angiogenic Gene Therapy. Save the Vessels, Save the Lung!
por: Zepp, Jarod A., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_1h9jbru7o8a9p7gm5rs6u7da40