Transcriptomic profiling identifies novel mechanisms of transcriptional regulation of the cytochrome P450 (Cyp)3a11 gene

Cytochrome P450 (CYP)3A is the most abundant CYP enzyme in the human liver, and a functional impairment of this enzyme leads to unanticipated adverse reactions and therapeutic failures; these reactions result in the early termination of drug development or the withdrawal of drugs from the market. Th...

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Detalles Bibliográficos
Autores principales: Taneja, Guncha, Maity, Suman, Jiang, Weiwu, Moorthy, Bhagavatula, Coarfa, Cristian, Ghose, Romi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491424/
https://www.ncbi.nlm.nih.gov/pubmed/31040347
http://dx.doi.org/10.1038/s41598-019-43248-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491424/
https://www.ncbi.nlm.nih.gov/pubmed/31040347
http://dx.doi.org/10.1038/s41598-019-43248-w

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