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Competitive non-SELEX for the selective and rapid enrichment of DNA aptamers and its use in electrochemical aptasensor

The SELEX (Systematic Evolution of Ligands by EXponential enrichment) method has been used successfully since 1990, but work is still required to obtain highly specific aptamers. Here, we present a novel approach called ‘Competitive non-SELEX’ (and termed as ‘SELCOS’ (Systematic Evolution of Ligands...

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Detalles Bibliográficos
Autores principales: Kushwaha, Ankita, Takamura, Yuzuru, Nishigaki, Koichi, Biyani, Manish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491428/
https://www.ncbi.nlm.nih.gov/pubmed/31040350
http://dx.doi.org/10.1038/s41598-019-43187-6