Human Pancreatic Carcinoma-Associated Fibroblasts Promote Expression of Co-inhibitory Markers on CD4(+) and CD8(+) T-Cells

Carcinoma-associated pancreatic fibroblasts (CAFs) are the major type of cells in the stroma of pancreatic ductal adenocarcinomas and besides their pathological release of extracellular matrix proteins, they are also perceived as key contributors to immune evasion. Despite the known relevance of tum...

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Detalles Bibliográficos
Autores principales: Gorchs, Laia, Fernández Moro, Carlos, Bankhead, Peter, Kern, Katharina P., Sadeak, Imrul, Meng, Qingda, Rangelova, Elena, Kaipe, Helen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491453/
https://www.ncbi.nlm.nih.gov/pubmed/31068935
http://dx.doi.org/10.3389/fimmu.2019.00847

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491453/
https://www.ncbi.nlm.nih.gov/pubmed/31068935
http://dx.doi.org/10.3389/fimmu.2019.00847

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