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Human Pancreatic Carcinoma-Associated Fibroblasts Promote Expression of Co-inhibitory Markers on CD4(+) and CD8(+) T-Cells
Carcinoma-associated pancreatic fibroblasts (CAFs) are the major type of cells in the stroma of pancreatic ductal adenocarcinomas and besides their pathological release of extracellular matrix proteins, they are also perceived as key contributors to immune evasion. Despite the known relevance of tum...
Autores principales: | Gorchs, Laia, Fernández Moro, Carlos, Bankhead, Peter, Kern, Katharina P., Sadeak, Imrul, Meng, Qingda, Rangelova, Elena, Kaipe, Helen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491453/ https://www.ncbi.nlm.nih.gov/pubmed/31068935 http://dx.doi.org/10.3389/fimmu.2019.00847 |
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