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Insulin Signaling Impairment in the Brain as a Risk Factor in Alzheimer’s Disease
Type 2 diabetes is a risk factor for developing Alzheimer’s disease (AD). The underlying mechanism that links up the two conditions seems to be the de-sensitization of insulin signaling. In patients with AD, insulin signaling was found to be de-sensitized in the brain, even if they did not have diab...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491455/ https://www.ncbi.nlm.nih.gov/pubmed/31068799 http://dx.doi.org/10.3389/fnagi.2019.00088 |