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CD38 in Adenosinergic Pathways and Metabolic Re-programming in Human Multiple Myeloma Cells: In-tandem Insights From Basic Science to Therapy

Tumor microenvironments are rich in extracellular nucleotides that can be metabolized by ectoenzymes to produce adenosine, a nucleoside involved in controlling immune responses. Multiple myeloma, a plasma cell malignancy developed within a bone marrow niche, exploits adenosinergic pathways to custom...

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Detalles Bibliográficos
Autores principales: Horenstein, Alberto L., Bracci, Cristiano, Morandi, Fabio, Malavasi, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491463/
https://www.ncbi.nlm.nih.gov/pubmed/31068926
http://dx.doi.org/10.3389/fimmu.2019.00760