FHL2 mediates podocyte Rac1 activation and foot process effacement in hypertensive nephropathy

RAAS inhibition has been the standard treatment for CKD for years because it can reduce proteinuria and hence retard renal function decline, but the proteinuria reduction effect is still insufficient in many patients. Podocyte foot process and slit diaphragm are the final barrier to prevent serum pr...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Szu-Yuan, Chu, Pao-Hsien, Huang, Po-Hsun, Hsieh, Tsung-Han, Susztak, Katalin, Tarng, Der-Cherng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491468/
https://www.ncbi.nlm.nih.gov/pubmed/31040292
http://dx.doi.org/10.1038/s41598-019-42328-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491468/
https://www.ncbi.nlm.nih.gov/pubmed/31040292
http://dx.doi.org/10.1038/s41598-019-42328-1

Ejemplares similares