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Effect of co-infection with a small intestine-restricted helminth pathogen on oral prion disease pathogenesis in mice

The early replication of some orally-acquired prion strains upon stromal-derived follicular dendritic cells (FDC) within the small intestinal Peyer’s patches is essential to establish host infection, and for the disease to efficiently spread to the brain. Factors that influence the early accumulatio...

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Detalles Bibliográficos
Autores principales: Sánchez-Quintero, Alejandra, Bradford, Barry M., Maizels, Rick, Donaldson, David S., Mabbott, Neil A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491469/
https://www.ncbi.nlm.nih.gov/pubmed/31040320
http://dx.doi.org/10.1038/s41598-019-42900-9