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Effect of co-infection with a small intestine-restricted helminth pathogen on oral prion disease pathogenesis in mice
The early replication of some orally-acquired prion strains upon stromal-derived follicular dendritic cells (FDC) within the small intestinal Peyer’s patches is essential to establish host infection, and for the disease to efficiently spread to the brain. Factors that influence the early accumulatio...
Autores principales: | Sánchez-Quintero, Alejandra, Bradford, Barry M., Maizels, Rick, Donaldson, David S., Mabbott, Neil A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491469/ https://www.ncbi.nlm.nih.gov/pubmed/31040320 http://dx.doi.org/10.1038/s41598-019-42900-9 |
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