Secreted parasite Pin1 isomerase stabilizes host PKM2 to reprogram host cell metabolism

Metabolic reprogramming is an important feature of host–pathogen interactions and a hallmark of tumorigenesis. The intracellular apicomplexa parasite Theileria induces a Warburg-like effect in host leukocytes by hijacking signaling machineries, epigenetic regulators and transcriptional programs to c...

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Detalles Bibliográficos
Autores principales: Marsolier, Justine, Perichon, Martine, Weitzman, Jonathan B., Medjkane, Souhila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491484/
https://www.ncbi.nlm.nih.gov/pubmed/31044177
http://dx.doi.org/10.1038/s42003-019-0386-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491484/
https://www.ncbi.nlm.nih.gov/pubmed/31044177
http://dx.doi.org/10.1038/s42003-019-0386-6

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